Tuermeric and Curcumin
Turmeric (Curcuma longa L.) a member of the ginger family is extensively used in Ayurveda, Chinese, Unani and Siddha medicine in India as traditional remedy for various diseases.
Curcumin is the principal curcuminoid in turmeric. Curcuminoids are polyphenolic compounds
that give turmeric its yellow color.
Learn what are the health benefits of Turmeric and Curcumin capsules
Turmeric and Curcumin has been shown to have a wide spectrum of biological actions.
Its anticancer effect is mainly mediated through induction of apoptosis.
Clinically, curcumin has already been used to reduce post-operative inflammation.
Safety evaluation studies indicate that both turmeric and curcumin are well tolerated at
very high dose without any toxic effects.
Thus, both turmeric and curcumin have the potential for the development of modern medicine for the treatment of various diseases.
Turmeric health benefits
Curcumin has a wide spectrum of efficiency.
It was found to fanction as:
Reduces cholesterol and blood lipids
Restores and protects the liver
Helps treat osteoarthritis and rheumatic
Helps manage diabetes
Curcumin exhibits low oral bioavailability and may undergo intestinal metabolism; absorbed curcumin undergoes rapid first-pass metabolism and excretion in the bile. In vivo studies show that less than 1% of the curcumin one consumes actually makes it into the bloodstream, and the liver rapidly destroys most of this.
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Turmeric and Curcumin health studies:
Indian J Pharmacol. 2015 Mar-Apr;47(2):160-6. doi: 10.4103/0253-7613.153422. Exploring the role of curcumin containing ethanolic extract obtained from Curcuma longa (rhizomes) against retardation of wound healing process by aspirin. Pawar RS1, Toppo FA1, Mandloi AS1, Shaikh S1.
J Mol Cell Cardiol. 2015 Feb;79:1-12. doi: 10.1016/j.yjmcc.2014.10.002. Epub 2014 Oct 16. Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo.
Harefuah. 2015 Jan;154(1):56-8, 66. Curcumin add-on therapy for ulcerative colitis.
Otol Neurotol. 2014 Jun;35(5):e169-77. Curcuma longa (curcumin) decreases in vivo cisplatin-induced ototoxicity through heme oxygenase-1 induction.Fetoni AR1, Eramo SL, Paciello F, Rolesi R, Podda MV, Troiani D, Paludetti G.
Cheng AL, Hsu CH, Lin JK, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001, 21, 2895–2900.
Ricky A. Sharma, Stephanie A. Euden, et al. Phase I Clinical Trial of Oral Curcumin Biomarkers of Systemic Activity and Compliance . Clinical Cancer Research 2004, 10, 6847-6854
2011 Nov;14(6):588-97. Curcuma as a functional food in the control
of cancer and inflammation.Schaffer M1, Schaffer PM, Zidan J, Bar Sela G